Beyond AlphaFold: ESMFold2 Launches with a 1‑Billion‑Protein Open Atlas

ESMFold2, an open‑source protein‑language‑model predictor, now offers predictions for 1 billion structures and a 6.8 billion‑sequence Atlas, delivering faster, more accurate antibody and protein‑interaction designs than AlphaFold3, while demonstrating experimental success and revealing novel CRISPR‑like proteins, though atypical cases still need careful validation.

AlphaFoldESM AtlasESMFold2

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Beyond AlphaFold: ESMFold2 Launches with a 1‑Billion‑Protein Open Atlas

HyperAI Super Neural

Mar 11, 2026 · Artificial Intelligence

Bi-TEAM Raises Hemolysis Prediction Accuracy 350% with Unified Biological‑Semantic and Chemical‑Precision Framework

Bi-TEAM, a cross‑scale representation learning framework that injects local chemical variations into a global protein context, outperforms state‑of‑the‑art baselines on ten biochemical datasets, achieving a 350% boost in hemolysis prediction accuracy and a 66% MCC increase under strict scaffold splits.

Bi-TEAMchemical modificationhemolysis prediction

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Bi-TEAM Raises Hemolysis Prediction Accuracy 350% with Unified Biological‑Semantic and Chemical‑Precision Framework